48 lines
No EOL
2.7 KiB
Markdown
48 lines
No EOL
2.7 KiB
Markdown
---
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title: Distractor-resistant short-term memory is supported by transient changes in neural
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stimulus representations
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persons:
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- michael-hanke
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topics:
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- neuroimaging
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- predictive-data-analysis
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params:
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graphRootNodePID: xyzrins:publications/0f4abbf1-099b-48b2-a1a1-79438c188aef
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pid: xyzrins:publications/0f4abbf1-099b-48b2-a1a1-79438c188aef
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doi: 10.1162/jocn_a_01141
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date: '2017-09-01'
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title: Distractor-resistant short-term memory is supported by transient changes in
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neural stimulus representations
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description: Goal-directed behavior in a complex world requires the maintenance of
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goal-relevant information despite multiple sources of distraction. However, the
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brain mechanisms underlying distractor-resistant working or short-term memory (STM)
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are not fully understood. Although early single-unit recordings in monkeys and fMRI
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studies in humans pointed to an involvement of lateral prefrontal cortices, more
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recent studies highlighted the importance of posterior cortices for the active maintenance
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of visual information also in the presence of distraction. Here, we used a delayed
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match-to-sample task and multivariate searchlight analyses of fMRI data to investigate
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STM maintenance across three extended delay phases. Participants maintained two
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samples (either faces or houses) across an unfilled pre-distractor delay, a distractor-filled
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delay, and an unfilled post-distractor delay. STM contents (faces vs. houses) could
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be decoded above-chance in all three delay phases from occipital, temporal, and
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posterior parietal areas. Classifiers trained to distinguish face versus house maintenance
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successfully generalized from pre- to post-distractor delays and vice versa, but
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not to the distractor delay period. Furthermore, classifier performance in all delay
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phases was correlated with behavioral performance in house, but not face, trials.
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Our results demonstrate the involvement of distributed posterior, but not lateral
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prefrontal, cortices in active maintenance during and after distraction. They also
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show that the neural code underlying STM maintenance is transiently changed in the
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presence of distractors and reinstated after distraction. The correlation with behavior
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suggests that active STM maintenance is particularly relevant in house trials, whereas
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face trials might rely more strongly on contributions from long-term memory.
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kind: bibo:AcademicArticle
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author:
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- pid: xyzrins:persons/michael-hanke
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given_name: Michael
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family_name: Hanke
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topic:
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- pid: xyzrins:topics/neuroimaging
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display_label: Neuroimaging
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- pid: xyzrins:topics/predictive-data-analysis
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display_label: Predictive data analysis
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--- |